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Rapid method for detection of point mutations using mismatch binding protein (MutS) and an optical biosensor
1Research and Development Department, Pharmacia Biotech KK, Tokyo, Japan.
Genetic Analysis : Biomolecular Engineering
|July 1, 1997
Abstract:
This paper describes a new method for detecting DNA point mutations using a mismatch binding protein. The interactions of mismatches and mismatch binding proteins are detected by the optical biosensor technology based on surface plasmon resonance (SPR).