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Causes of enucleation: a clinicopathological study
1Ocular Oncology Department, Faculty of Medicine, Ankara University, Turkey.
European Journal of Ophthalmology
|July 1, 1997
Summary
Enucleation rates for several eye conditions decreased due to improved treatments, but tumor-related enucleations increased. Early diagnosis of intraocular tumors is crucial to reduce enucleations.
Area of Science:
- Ophthalmology
- Ocular Pathology
- Surgical Interventions
Background:
- Enucleation addresses end-stage ocular diseases causing blindness, pain, or cosmetic issues.
- This study analyzes trends and causes of eye enucleations over five decades.
Purpose of the Study:
- To investigate the changing patterns and primary causes of enucleation from 1945 to 1995.
- To identify demographic and etiological factors influencing enucleation rates.
Main Methods:
- Retrospective review of clinicopathological data from 3506 enucleations.
- Categorization of causes into eight groups: trauma, phthisis, corneal disease, inflammation, vitreoretinal disease, glaucoma, tumors, and infections.
Main Results:
- Tumors were the leading cause (33.8%), followed by phthisis (16.7%) and glaucoma (16.0%).
- Enucleations were more common in males for infections, trauma, and inflammation; more common in females for tumors.
- A significant decrease in enucleations for phthisis, infections, corneal diseases, trauma, and inflammation was observed from 1986-1995 compared to 1976-1985.
Conclusions:
- Advances in diagnostics and treatments have reduced enucleation frequency for many conditions.
- Increased enucleations for tumors highlight the need for prompt diagnosis and intervention.
- Early detection of intraocular tumors can potentially decrease the necessity for enucleation.