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Influence of optic and haptic materials on the adherence of Staphylococcus epidermidis to intraocular lenses: a pilot

G Prosdocimo1, S Grandesso, G Amici

  • 1Ophthalmology Division, ULSS no. 7, Conegliano (TV), Italy.

European Journal of Ophthalmology
|July 1, 1997
PubMed

Insights

This study assessed Staphylococcus epidermidis adherence to various intraocular lens (IOL) materials. All-polymethylmethacrylate (PMMA) IOLs demonstrated the best resistance to bacterial adherence in vitro.

Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Microbiology

Background:

  • Bacterial adherence to intraocular lenses (IOLs) is a significant risk factor for postoperative endophthalmitis.
  • Understanding material-specific bacterial adhesion is crucial for preventing IOL-related infections.

Purpose of the Study:

  • To compare the in vitro adherence of Staphylococcus epidermidis to IOLs made from different optic and haptic materials.
  • To identify IOL materials with superior resistance to bacterial colonization.

Main Methods:

  • A quantitative cultural method was employed to assess bacterial adherence.
  • Tested IOL materials included polymethylmethacrylate (PMMA), PMMA-prolene, polyHEMA, silicone, and surface-modified PMMA (wet and dry).

Main Results:

  • Significant differences in Staphylococcus epidermidis adherence were observed across the tested IOL material groups.
  • Intraocular lenses composed entirely of PMMA exhibited the lowest bacterial adherence.

Conclusions:

  • The material composition of intraocular lenses significantly influences Staphylococcus epidermidis adherence.
  • All-PMMA IOLs present a promising option for reducing the risk of bacterial colonization and subsequent infection.

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