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Related Experiment Videos

Normal placenta: gadolinium-enhanced dynamic MR imaging

H B Marcos1, R C Semelka, S Worawattanakul

  • 1Department of Radiology, University of North Carolina, Chapel Hill 27599-7510, USA.

Radiology
|November 14, 1997
PubMed
Summary
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Dynamic, gadolinium-enhanced MRI reveals normal placental enhancement is intense and rapid, preceding myometrial enhancement. Third-trimester placentas show lobular enhancement, while second-trimester placentas appear heterogeneous.

Area of Science:

  • Radiology
  • Medical Imaging
  • Obstetrics

Background:

  • Dynamic, gadolinium-enhanced magnetic resonance (MR) imaging is a valuable tool for evaluating placental abnormalities.
  • Understanding the normal placental enhancement patterns is crucial for accurate diagnosis.

Purpose of the Study:

  • To establish the typical appearance of the normal placenta on dynamic, gadolinium-enhanced MR images.
  • To characterize placental enhancement patterns in relation to myometrial enhancement.

Main Methods:

  • Eleven patients with suspected uterine or placental abnormalities underwent MR imaging.
  • T1-weighted, fat-suppressed, spoiled gradient-recalled-echo (GRE) and T2-weighted, half-Fourier, single-shot, spin-echo-train (HASTE) sequences were acquired.
  • Two investigators retrospectively evaluated placental and myometrial enhancement patterns.

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Main Results:

  • The placenta demonstrated rapid and intense enhancement immediately post-contrast, preceding myometrial enhancement.
  • Third-trimester placentas showed closely packed lobules (2-3 cm) of enhancement.
  • Second-trimester placentas exhibited heterogeneous enhancement, becoming more homogeneous over time.

Conclusions:

  • Normal placental enhancement is intense and occurs earlier than myometrial enhancement on dynamic contrast-enhanced MR imaging.
  • Distinct enhancement patterns (lobular vs. heterogeneous) are observed in the third and second trimesters, respectively.