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Evaluation for malignant hyperthermia susceptibility in black-tailed deer
J F Antognini1, P H Eisele, G A Gronert
1Department of Anesthesiology, University of California, Davis 95616, USA.
Journal of Wildlife Diseases
|October 1, 1996
Summary
This study found no evidence of malignant hyperthermia in black-tailed deer challenged with anesthetics, suggesting no link between malignant hyperthermia and capture myopathy in this species.
Area of Science:
- Veterinary Anesthesiology
- Wildlife Physiology
Background:
- Capture myopathy is a concern in wild animals.
- Malignant hyperthermia is a rare, severe reaction to anesthesia.
Purpose of the Study:
- To investigate a potential link between malignant hyperthermia and capture myopathy in black-tailed deer.
Main Methods:
- Four black-tailed deer were anesthetized and challenged with halothane and succinylcholine.
- Cardiac output and oxygen consumption were monitored.
- Muscle biopsy specimens were tested for susceptibility to malignant hyperthermia.
Main Results:
- Succinylcholine significantly increased cardiac output and oxygen consumption.
- Halothane did not significantly affect oxygen consumption.
- Muscle biopsies showed normal responses to halothane and caffeine, indicating no malignant hyperthermia susceptibility.
Conclusions:
- The challenged deer did not exhibit signs of malignant hyperthermia.
- The findings suggest no direct link between malignant hyperthermia and capture myopathy in black-tailed deer.