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Reliability of a comorbidity measure: the Index of Co-Existent Disease (ICED)

K Imamura1, M McKinnon, R Middleton

  • 1Dept. of Public Health and Policy, London School of Hygiene & Tropical Medicine, UK.

Insights

The Index of Co-Existent Disease (ICED) shows moderate reliability for assessing comorbidities in elderly hip replacement patients. Improving ICED instructions is crucial for consistent application in retrospective data analysis.

Area of Science:

  • Geriatric Medicine
  • Health Services Research
  • Medical Informatics

Background:

  • Comorbidity indices are vital for predicting patient outcomes and guiding clinical decisions.
  • The Index of Co-Existent Disease (ICED) is an established tool for quantifying patient comorbidities.
  • Accurate comorbidity assessment is essential, particularly in elderly populations undergoing major surgery.

Purpose of the Study:

  • To evaluate the inter-rater and intra-rater reliability of the Index of Co-Existent Disease (ICED).
  • To assess the reliability of the ICED using retrospective data from elderly patients undergoing total hip replacement.
  • To identify factors contributing to the reliability of the ICED in clinical practice.

Main Methods:

  • Retrospective analysis of case notes from elderly patients who underwent total hip replacement.
  • Two inter-rater reliability assessments with two and three raters, respectively.
  • One intra-rater reliability assessment using a single rater.

Main Results:

  • Moderate inter-rater reliability for the overall ICED (kappa 0.5-0.6).
  • Excellent intra-rater reliability (kappa 0.9).
  • The Functional Severity subindex showed good reliability (kappa 0.6-1.0), while the Index of Disease Severity subindex had lower reliability (kappa 0.4-0.5).
  • Rater discrepancies influenced the association between comorbidity and post-operative complications.

Conclusions:

  • The ICED demonstrates moderate reliability in assessing comorbidities, with significant variations in inter-rater consistency.
  • Intra-rater reliability is high, suggesting individual raters can apply the index consistently.
  • Enhancements to ICED instructions are necessary to improve inter-rater reliability for retrospective data analysis.

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