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Developmental aspects of sleep and breathing
1Stanford University Sleep Disorders Center, CA 94305, USA.
Current Opinion in Pulmonary Medicine
|November 1, 1996
Summary
This report links sleep research and developmental pulmonology, detailing the development of sleep and breathing from infancy to adulthood. It explores sleep-disordered breathing, its childhood origins, and familial links to sudden infant death syndrome.
Area of Science:
- Integrative physiology
- Developmental biology
- Pulmonology
Background:
- Sleep and breathing development are often studied separately.
- Existing research combines basic physiology with newer pathophysiological insights.
- Developmental abnormalities can manifest across the lifespan.
Purpose of the Study:
- To comprehensively describe the development and control of sleep and breathing from gestation through adulthood.
- To link sleep research and developmental pulmonology.
- To detail pathophysiological mechanisms of sleep-disordered breathing.
Main Methods:
- Literature review and synthesis of existing research.
- Integration of basic physiological data with clinical observations.
- Analysis of developmental trajectories in sleep and breathing control.
Main Results:
- Sleep and breathing control develop intricately from gestation to adulthood.
- Sleep-disordered breathing has developmental origins in childhood that can persist or reappear in adulthood.
- Familial and genetic factors contribute to sleep-disordered breathing.
Conclusions:
- A unified understanding of sleep and breathing development is crucial.
- Childhood developmental issues can underlie adult sleep-disordered breathing.
- Sleep-disordered breathing, including sudden infant death syndrome, has significant familial and genetic components.