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Microalbuminuria in early pregnancy in normal and high-risk patients

J Bar1, M Hod, A Erman

  • 1Department of Obstetrics and Gynecology, Rabin Medical Center, Petah Tiqva, Israel.

Early Pregnancy : Biology and Medicine : the Official Journal of the Society for the Investigation of Early Pregnancy
|September 1, 1996
PubMed

The albumin excretion rate (AER) is elevated in normal pregnant women in the third trimester of pregnancy, compared to the second and first trimesters, and to the non-pregnant state. The effect of early pregnancy on AER values was tested in normal and high-risk pregnant patients using radioimmunoassay. All pregnant patients demonstrated significantly higher AER values as compared to non-pregnant women, and the results were in correlation with higher urinary creatinine clearance values. The appearance of microalbuminuria in the first trimester can indicate underlying renal damage in patients at high risk of hypertensive complications.

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