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"Mixed dementia": adequate or antiquated? A critical review
Abstract:
Despite its importance and widespread usage, the term mixed dementia, referring to the coexistence of Alzheimer's disease (AD) and vascular dementia (VsD), has been ill-defined and poorly conceptualized. The authors review the use of the term mixed dementia in neuropathological and clinical research. As a result of recent developments in the categorization of dementias, they recommend discarding the term mixed dementia in favor of a more precise terminology based on AD and VsD concurrently meeting established criteria for each diagnosis.
Insights
The term mixed dementia is poorly defined. Researchers recommend replacing it with precise diagnoses of Alzheimer's disease and vascular dementia when both conditions are present.
Area of Science:
- Neurology
- Gerontology
- Pathology
Background:
- The term "mixed dementia" is commonly used but lacks clear definition.
- It refers to the co-occurrence of Alzheimer's disease (AD) and vascular dementia (VsD).
- Current conceptualization and usage in research are inconsistent.