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Related Experiment Videos

Left ventricular geometry in presenting untreated hypertension

J Mayet1, M Shahi, N R Poulter

  • 1Department of Cardiology, Imperial College, St Mary's Hospital, London, UK.

Journal of Human Hypertension
|November 19, 1997
PubMed
Summary

Untreated hypertension significantly alters left ventricular (LV) geometry, with most patients showing concentric hypertrophy or remodelling. Sphericity remained consistent, but eccentric hypertrophy was less common in this population.

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Hypertension Research

Background:

  • Left ventricular (LV) geometry is crucial in hypertension.
  • Understanding geometric patterns aids in risk stratification and treatment.
  • Previous studies show varied geometric distributions in hypertensive patients.

Purpose of the Study:

  • To investigate the spectrum of left ventricular geometry in untreated hypertensive patients.
  • To assess LV mass index, relative wall thickness, and sphericity.
  • To compare findings with previously published data.

Main Methods:

  • Two-dimensional echocardiography was performed on 63 untreated hypertensive patients.
  • Calculated LV mass index and relative wall thickness from M-mode.

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  • Assessed LV sphericity using the ratio of LV minor to major hemiaxis.
  • Main Results:

    • Concentric hypertrophy (46%) and concentric remodelling (32%) were the most prevalent geometric patterns.
    • Eccentric hypertrophy (6%) and normal LV shape (16%) were less common.
    • LV sphericity was similar across ethnic groups and did not change in uncomplicated hypertension.

    Conclusions:

    • Untreated hypertension predominantly leads to concentric LV hypertrophy or remodelling.
    • The low proportion of eccentric hypertrophy may be linked to the high prevalence of Afro-Caribbean subjects.
    • LV sphericity appears stable in uncomplicated hypertension, irrespective of ethnicity.