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Related Experiment Videos

The andropause: fact or fiction?

N Burns-Cox1, C Gingell

  • 1Bristol Urological Institute, Southmead Hospital, UK.

Postgraduate Medical Journal
|November 28, 1997
PubMed
Summary

Testosterone supplementation for andropause symptoms in men with normal hormone levels lacks scientific evidence. Benefits are equivocal, with no proven effects on erectile dysfunction or other health markers.

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Area of Science:

  • Andrology
  • Endocrinology
  • Men's Health

Background:

  • Andropause is an ill-defined condition in men with variable androgen levels.
  • Testosterone replacement therapy (TRT) benefits in men are equivocal, unlike in women.

Purpose of the Study:

  • To evaluate the efficacy of testosterone supplementation for symptoms attributed to andropause in men.
  • To differentiate between hypogonadal and eugonadal men regarding TRT benefits.

Main Methods:

  • Review of existing scientific literature and clinical studies on testosterone supplementation.
  • Analysis of placebo-controlled studies investigating TRT for andropause symptoms.

Main Results:

  • Testosterone supplementation may slightly increase sexual interest but rarely to patient satisfaction.
  • No proven benefits for erectile dysfunction, haemopoesis, bone metabolism, lipids, or fibrinolysis.
  • TRT is beneficial for hypogonadal men but not for eugonadal men with andropause symptoms.

Conclusions:

  • Symptoms like fatigue in eugonadal men are likely due to stress, not low testosterone.
  • There is no scientifically valid evidence supporting testosterone supplements for eugonadal men experiencing andropause symptoms.

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