Tissue culture studies of contact lenses

Standard methylmethacrylate hard contact lenses and several available soft (HEMA) contact lenses were studied in tissue culture using secondary rabbit kidney cells. No toxic constituents were found but the cells were readily destroyed by a keratoprosthesis which was found to be toxic in culture. The tissue culture technique should assist in determining which plastics are most suitable for in vivo use and make conclusions concerning mechanical or metabolic effects of lenses more meaningful.