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Prosthesis for aortic arch substitution

S Nazari1, S Salvi, A Aluffi

  • 1Department of Surgery, University of Pavia, Istituto di Ricovero e Cura a Carattere Scientifico San Matteo, Italy.

The Annals of Thoracic Surgery
|December 5, 1997
PubMed
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A novel device significantly reduces aortic arch substitution time, minimizing neurologic risks. This innovation simplifies vascular anastomosis, improving patient outcomes in complex aortic surgeries.

Area of Science:

  • Cardiovascular Surgery
  • Biomedical Engineering
  • Surgical Devices

Background:

  • Neurologic complications in aortic arch prosthetic substitution correlate with circulatory arrest duration.
  • Current methods for aortic arch repair can involve prolonged circulatory arrest times.
  • Simplifying and accelerating vascular anastomosis is crucial for reducing surgical risks.

Purpose of the Study:

  • To evaluate a novel device designed to simplify and expedite vascular anastomosis during aortic arch substitution.
  • To assess the efficacy and safety of this device in animal models.
  • To explore potential benefits for clinical application in aortic arch surgery.

Main Methods:

  • A Dacron prosthesis was modified with expandable stainless steel wire loops and a removable guide for diameter control.

Related Experiment Videos

  • The device was integrated into a composite graft for supraaortic trunk branches.
  • Acute experiments were conducted in 5 swine utilizing cardiopulmonary bypass and brief hypothermic circulatory arrest.

    • Main Results:

    • Four out of five swine survived the procedure without neurological complications.
    • The prosthesis was correctly positioned post-procedure.
    • No lumen distortion or thrombosis was observed at sacrifice.

    Conclusions:

    • The device facilitates rapid and secure vascular anastomosis in aortic arch substitution.
    • Potential clinical advantages include reduced circulatory arrest time and improved hemostasis.
    • This approach may enhance approximation of tissue layers, particularly in dissecting aneurysms.