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Endometriosis in monozygotic twins
R M Hadfield1, H J Mardon, D H Barlow
1Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital, United Kingdom.
Fertility and Sterility
|December 9, 1997
Abstract
Objective:
To describe the occurrence of endometriosis in monozygotic twins.
Design:
Postal questionnaire plus confirmation of disease status.
Setting:
Twins were recruited via the American Endometriosis Association and the National Endometriosis Society of Great Britain and via British gynecologists.
Result(S):
Fourteen twin pairs were concordant for endometriosis, and two were discordant. Nine pairs of twins had moderate-severe endometriosis.
Conclusion(S):
These findings contribute to the growing body of literature that suggests endometriosis has a genetic basis.