Carbon dioxide laser for cutaneous melanoma metastases: indications and limitations

A total of 469 in-transit or satellite lesions were treated by carbon dioxide (CO2) laser vaporization in 15 patients. The treatment was performed mostly on an outpatient basis, under local anaesthesia. The technique was easily mastered and quickly performed. Wound healing and patient acceptance were good. A major drawback, however, proved to be the unexpected high incidence of recurrences at the lasered sites. In our opinion CO2 laser treatment may be considered as a palliative option in patients with a moderate to extensive amount of cutaneous metastases, whose lesions preferably are < 10 mm and in whom local excision is not feasible anymore. For extremity lesions this treatment may have a place after failure of isolated limb perfusion. CO2 laser treatment cannot be considered a first-line option unless the issue of local recurrences is solved.