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[Male pseudohermaphroditism]

¹Department of Urology, Asoka Hospital.

Nihon Rinsho. Japanese Journal of Clinical Medicine

|December 13, 1997

Summary

This summary is machine-generated.

Male pseudohermaphroditism involves incomplete masculinization despite testes presence, stemming from embryonic testicular development failures. This condition is categorized by various etiological factors impacting male sex differentiation.

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Area of Science:

Reproductive biology
Developmental biology
Endocrinology

Context:

Male pseudohermaphroditism is a disorder of sex differentiation.
Characterized by testes presence with incomplete masculinization of internal and external genitalia.
Results from failures in embryonic testicular development processes.

Purpose:

To define male pseudohermaphroditism.
To outline the embryological basis of the condition.
To categorize the etiological factors contributing to male pseudohermaphroditism.

Summary:

Male pseudohermaphroditism presents with testes but incompletely masculinized genital ducts and external genitalia.
It arises from disruptions in the sequential embryonic development of the testis.

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Classified into subtypes based on etiological factors including hormonal unresponsiveness, biosynthesis defects, androgen resistance, and organogenesis issues.

Impact:

Provides a clear definition and classification of male pseudohermaphroditism.
Highlights the critical role of embryonic testicular development in male sexual differentiation.
Establishes a framework for understanding the diverse causes of this condition.