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The non-redundant Bacillus subtilis (NRSub) database: update 1998
G Perrière1, M Gouy, T Gojobori
1Laboratoire de Biométrie, Génétique et Biologie des Populations, Université Claude Bernard, Lyon 1, 43 boulevard du 11 Novembre 1918, 69622 Villeurbanne Cedex, France. perriere@biomserv.univ-lyon.fr
Nucleic Acids Research
|February 21, 1998
Summary
The non-redundant Bacillus subtilis database (NRSub) provides comprehensive genomic information for this bacterium. This resource facilitates access to individual functional regions and detailed gene annotations for researchers.
Area of Science:
- Microbiology
- Bioinformatics
- Genomics
Background:
- The Bacillus subtilis genome sequencing project is complete, yielding a single contiguous sequence.
- Existing databases may lack comprehensive, integrated annotation for B. subtilis.
Purpose of the Study:
- To develop and present the non-redundant Bacillus subtilis database (NRSub).
- To provide researchers with individual access to functional genomic regions and enhanced annotations.
Main Methods:
- Utilized the ACNUC database management system and Query_win retrieval system.
- Integrated additional annotations including gene accession numbers, genetic map locations, and codon adaptation index values.
- Established cross-references with other biological collections.
Main Results:
- NRSub offers individual access to functional genomic regions of Bacillus subtilis.
- Enhanced annotations provide detailed information for each gene.
- The database is accessible via anonymous FTP and dedicated World Wide Web servers.
Conclusions:
- NRSub serves as a valuable, centralized resource for Bacillus subtilis genomics research.
- The database enhances data accessibility and facilitates further biological investigation.