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Structural property and in vitro self-assembly of shark type I collagen
Y Nomura1, M Yamano, C Hayakawa
1Faculty of Agriculture, Tokyo University of Agriculture and Technology, Japan. ny318@cc.tuat.ac.jp
Bioscience, Biotechnology, and Biochemistry
|December 24, 1997
Abstract:
The main structure of shark type I collagen is similar to that of land mammals, with a partial difference in amino acid sequence and post-translational modification. By static light scattering, the weight-average molecular weight of shark collagen (7.52 x 10(5)) suggests the presence of some aggregated molecules, oligomeric collagen. The self-assembly curve of shark collagen had a shorter lag phase and a longer growth phase than that of pig collagen. The optimum temperature and pH of shark collagen self-assembly is different from that of pig collagen.