Penetrating keratoplasty for pseudophakic bullous keratopathy

Corneal decompensation after cataract surgery and intraocular lens (IOL) implantation has become the leading indication for penetrating keratoplasty during the past decade. We reviewed the clinical course and the surgical management of 212 patients with penetrating keratoplasty for pseudophakic bullous keratopathy treated at our Department during the last 15 years. Corneal transplantation for pseudophakic bullous keratopathy was successful in 76%. One third of the patients achieved a long-term visual acuity of 0.5 and more. At keratoplasty the original IOL was left in place in 129 eyes. We removed from and not replaced the IOL in 37 eyes and we performed IOL exchange in 46 eyes. The secondary IOL was an angle-supported flexible anterior chamber lens in 40 cases, and a suture fixated posterior chamber lens in 8 cases. During the penetrating keratoplasty for pseudophakic bullous keratopathy the most important question is how to manage the previously implanted intraocular lens. We have to decide whether the intraocular lens should be removed or replaced at the time of surgery. The choice of removing, retaining or replacing the intraocular lens at keratoplasty depends on the variable intraocular pathological conditions and each case requires individual evaluation.