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Renal SPECT with Tc-99m DMSA in children with upper urinary tract infections using a triple-headed gamma camera
B Bagni1, P Orsolon, A Fattori
1Department of Medical and Radiological Science, University of Modena, Italy.
Insights
Single-photon emission computed tomography (SPECT) scanning is superior to planar scintigraphy for detecting kidney lesions in children with urinary tract infections (UTI). SPECT identified more lesions, aiding in assessing cortical damage.
Area of Science:
- Nuclear Medicine
- Pediatric Nephrology
- Diagnostic Imaging
Background:
- Renal cortical scintigraphy using Tc-99m DMSA is valuable for assessing kidney damage from upper urinary tract infections (UTI).
- Understanding the extent of renal cortical damage is crucial for managing pediatric UTI and preventing long-term complications.
Purpose of the Study:
- To compare the efficacy of single-photon emission computed tomography (SPECT) versus planar scintigraphy in detecting renal lesions in children with UTI.
- To evaluate the diagnostic performance of SPECT in identifying cortical damage secondary to UTI.
Main Methods:
- Evaluation of 48 children diagnosed with UTI, including 12 with a history of vesicoureteral reflux.
- Utilized planar scintigraphy and SPECT imaging with a triple-headed gamma camera and high-resolution collimators.
Main Results:
- SPECT imaging detected positive findings in 36 kidneys, compared to 18 kidneys with planar scans.
- SPECT identified a total of 51 lesions, while planar scintigraphy detected only 23 lesions.
Conclusions:
- SPECT scanning demonstrates superior sensitivity in detecting kidney lesions in pediatric UTI cases.
- The findings support the use of SPECT as a more effective imaging modality for assessing renal cortical damage in children with UTI.
Unlabelled:
Renal cortical scintigraphy with Tc-99m DMSA provides an excellent imaging modality for the assessment of cortical damage secondary to upper urinary tract infection (UTI).
Methods:
The authors evaluated 48 children with UTI, 12 of whom had a history of vescico-ureteral reflux (from first of fourth degree), by planar scintigraphy and SPECT using a triple-headed gamma camera equipped with parallel-hole, high-resolution collimators.
Results:
SPECT images yielded positive findings in 36 kidneys, whereas planar scans yielded positive findings in 18 kidneys. The total number of lesions detected by SPECT was 51, whereas the number found with the planar technique was 23.
Conclusion:
This study demonstrates the superiority of SPECT scanning in detecting kidney lesions in children with UTI.