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[A long experience in basic therapy of rheumatoid arthritis]
1Kafedra vnutrennikh bolezneĭ No. 3 Pervogo lechebnogo fakulteta MMA im. I.M. Sechenova na baze gorodskoĭ klinicheskoĭ bol'nitsy No. 20, Moskva.
Klinicheskaia Meditsina
|January 1, 1997
Summary
This study followed 183 rheumatoid arthritis patients for over 13 years, examining mortality, tumors, and complications. Glucocorticoid use in 55 patients was specifically analyzed for adverse effects.
Area of Science:
- Rheumatology
- Clinical Medicine
- Longitudinal Studies
Context:
- Rheumatoid arthritis (RA) management involves long-term basic drug therapy.
- Understanding the long-term outcomes of RA patients is crucial for optimizing treatment strategies.
- Previous research has not fully elucidated the comprehensive long-term effects of RA treatment.
Purpose:
- To investigate the long-term mortality, causes of death, and overall complications in patients with rheumatoid arthritis (RA) undergoing basic drug treatment.
- To specifically analyze the impact of glucocorticoid use on complications in a subset of RA patients.
- To provide a comprehensive review of clinical, laboratory, instrumental, and morphological findings over an extended follow-up period.
Summary:
- A cohort of 183 rheumatoid arthritis patients received basic drugs for 3-15 years, with an average follow-up of 13.5 years.
- The study utilized diverse methods including clinical, laboratory, instrumental, and morphological assessments.
- Findings cover mortality rates, causes of death, incidence of lethal tumors, and overall complications, with a focus on 55 patients using glucocorticoids.
Impact:
- Provides critical data on the long-term prognosis and potential complications associated with rheumatoid arthritis treatment.
- Informs clinical decision-making regarding the use of basic drugs and glucocorticoids in RA management.
- Highlights the importance of long-term monitoring and comprehensive assessment in patients with chronic inflammatory diseases like RA.