Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Developmental constraints in the Drosophila wing

D Guerra1, M C Pezzoli, G Giorgi

  • 1Dipartimento di Biologia evol. sper., Università di Bologna, Italy.

Heredity
|January 7, 1998
PubMed
Summary

Selection experiments on Drosophila melanogaster wing veins reveal developmental constraints. Local changes are integrated predictably within the wing

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Black Hole Spectroscopy and Tests of General Relativity with GW250114.

Physical review letters·2026
Same author

GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

Physical review letters·2025
Same author

Intraoperative methylene blue staining is effective as a single mapping technique in the identification of sentinel lymph nodes in dogs with low-grade mast cell tumours.

The Journal of small animal practice·2025
Same author

Floating offshore wind potential for Mediterranean countries.

Heliyon·2024
Same author

Frequency-Dependent Squeezed Vacuum Source for the Advanced Virgo Gravitational-Wave Detector.

Physical review letters·2023
Same author

Proteomic analysis of the effect of hemin in breast cancer.

Scientific reports·2023

Area of Science:

  • Developmental biology
  • Evolutionary genetics
  • Drosophila melanogaster research

Background:

  • Understanding how genetic changes integrate into complex developmental programs is crucial.
  • Drosophila melanogaster serves as a model organism for studying wing development.

Purpose of the Study:

  • To investigate the integration of local genetic changes within the broader developmental program of Drosophila melanogaster wing venation.
  • To evaluate the constraints on evolutionary adaptation in wing development.

Main Methods:

  • Performed artificial selection experiments on a wild population of Drosophila melanogaster.
  • Focused selection on shortening the four longitudinal wing veins.

Main Results:

  • Demonstrated that despite potential multiple units of selection, developmental programs strongly constrain evolutionary trajectories.
  • Observed that only predictable phenotypic forms arise from selection pressures.
  • Results support the 'Entelechia' model of development.

Conclusions:

  • Developmental constraints dictate the range of possible evolutionary outcomes in wing vein formation.
  • Positional values, influenced by 'martial' genes, drive controlled cell proliferation and shape predictable forms.
  • The 'Entelechia' model provides a framework for understanding developmental integration and evolutionary predictability.

Related Experiment Videos