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Decidual leukocyte populations in ectopic pregnancies
A M Stewart-Akers1, J S Krasnow, J A DeLoia
1University of Pittsburgh, Pennsylvania, USA.
Objective:
To determine whether the recruitment of decidual leukocytes during pregnancy is the same in intrauterine pregnancies (IUPs) versus ectopic pregnancies (EPs).
Design:
Intrauterine decidual samples from both EPs and IUPs were obtained for the evaluation of leukocyte populations.
Setting:
In vitro experiment.
Patient(S):
Women with EPs and women with IUPs.
Main Outcome Measure(S):
Immunohistochemical identification of decidual leukocyte populations.
Result(S):
We have analyzed the decidual leukocyte populations from three women with EPs by immunohistochemical analysis. The data demonstrate a leukocyte infiltration similar to that found in decidua from normal pregnancies.
Conclusions(S):
These data support the hypothesis that decidual leukocyte recruitment and/or increases during pregnancy is primarily hormonally regulated.