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Related Experiment Videos

Use of a screening RAST in a large neuro-otologic practice

B K Howard, R L Mabry, W L Meyerhoff

    Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
    |January 7, 1998
    PubMed
    Summary
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    Nearly 40% of patients with neuro-otologic symptoms showed signs of inhalant allergy, a rate double the general population. Allergy screening is crucial for diagnosing inner ear and eustachian tube disorders.

    Area of Science:

    • Immunology
    • Otolaryngology
    • Allergy

    Background:

    • The immune system plays a role in inner ear and eustachian tube disorders.
    • Inhalant allergy is a potential, yet often overlooked, contributing factor to otologic conditions.

    Purpose of the Study:

    • To investigate the prevalence of inhalant allergy in patients presenting with neuro-otologic symptoms.
    • To determine if allergy screening is a valuable diagnostic tool for these patients.

    Main Methods:

    • A 2-year study involving 186 patients with neuro-otologic complaints.
    • Screening for immunoglobulin E-mediated hypersensitivity using radioallergosorbent testing (RAST).
    • Patients were selected based on otologic symptoms, not sinonasal issues.

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    Main Results:

    • Nearly 40% of selected patients tested positive for inhalant allergy.
    • This prevalence is more than double that of the general population.
    • A high incidence of mold antigen atopy was observed in this patient group.

    Conclusions:

    • Allergy significantly contributes to various otologic symptoms like vertigo, tinnitus, hearing loss, and eustachian tube dysfunction.
    • Screening for inhalant allergy, alongside clinical evaluation, is an effective method for comprehensive otologic workups.
    • Allergy is a notable etiologic factor in some cases of Meniere's syndrome.