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Correlation of total-body bone mineral content determined by dual-energy X-ray absorptiometry with bone mineral
M Revilla1, J L Cardenas, E R Hernández
1Department of Medicine, Universidad de Alcalá de Henares, Madrid, Spain.
Rationale And Objectives:
We sought to determine the value of peripheral quantitative computed tomography (pQCT) in measuring bone mineral density.
Methods:
In 50 healthy, eugonodal premenopausal women, we correlated measurements of total bone mineral content (BMCTB), made with dual-energy X-ray absorptiometry (DXA), and bone mineral density, determined by pQCT.
Results:
The partial correlations, adjusted for weight and age, between BMCTB and cortical bone density, total bone density, and trabecular bone density were .71 (p < .0001), .63 (p < .0001), and .32 (p < .05), respectively.
Conclusion:
These results and the advantages of pQCT--providing precise bone density determinations for trabecular and compact bone separately, having a high spatial resolution that allows a "compartmental" analysis of bone structure, having a low coefficient of variation, and having a minimal radiation dose (< 5 mrem)--confirm the adequacy of using this method for bone mass studies.