Cognitive side effects of medications
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Updated: Oct 22, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
Published on: April 23, 2014
1Department of Neurology, Medical College of Georgia, Augusta, Georgia 30912, USA.
Abstract:
Iatrogenically induced cognitive deficits are common with pharmacological therapy. The deficits may range from gross encephalopathy with delirium to subtle subjective alterations (e.g., mood and perception of well being). The risks are increased for certain drug types, polypharmacy, the elderly, and patients with dementia or metabolic abnormalities. This review examines methodological concerns and the neuropsychological data on cognitive side effects across a variety of commonly used medicines in clinical practice.
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