Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Rocuronium]

J A Alvarez-Gómez1

  • 1Servicio de Anestesia-Reanimación, Hospital Santa María del Rosell, Cartagena, Murcia.

Revista Espanola De Anestesiologia Y Reanimacion
|January 10, 1998
PubMed
Summary
This summary is machine-generated.

Rocuronium, a new neuromuscular blocking agent, offers rapid onset for intubation and lacks active metabolites. It provides hemodynamic stability, making it suitable for high-risk patients and various surgical procedures.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lithospheric folding by flexural slip in subduction zones as source for reverse fault intraslab earthquakes.

Scientific reports·2018
Same author

[Sugammadex: a new approach to the use of neuromuscular blockers].

Revista espanola de anestesiologia y reanimacion·2011
Same author

[Efficacy of sugammadex in the reversal of neuromuscular blockade induced by rocuronium in long-duration surgery: under inhaled vs. intravenous anesthesia].

Revista espanola de anestesiologia y reanimacion·2009
Same author

The cuff method: a pilot study of a new method of monitoring neuromuscular function.

Acta anaesthesiologica Scandinavica·2005
Same author

[Speed of intubation using a new neuromuscular blocker. Rocuronium bromide (ORG 9426)].

Revista espanola de anestesiologia y reanimacion·1994
Same author

Pharmacokinetics and pharmacodynamics of rocuronium bromide in adult patients.

European journal of anaesthesiology. Supplement·1994
Same journal

RICA Pathway (Enhanced Recovery After Surgery for Adults). 2026 Update: Executive Summary.

Revista espanola de anestesiologia y reanimacion·2026
Same journal

Viscoelastic testing: an essential tool for an efficient health system.

Revista espanola de anestesiologia y reanimacion·2026
Same journal

Therapeutic monitoring of beta-lactams in critically ill patients with sepsis: Clinical trial protocol.

Revista espanola de anestesiologia y reanimacion·2026
Same journal

Intraoperative haemodynamic support intensity as a marker of perioperative complexity and hospital resource utilization in noncardiac surgery.

Revista espanola de anestesiologia y reanimacion·2026
Same journal

Investigation of dye spread following ultrasound guided injection at the femoral nerve, proximal and distal adductor canal - A cadaver study.

Revista espanola de anestesiologia y reanimacion·2026
Same journal

Endotracheal tube-esophageal stent interaction in tracheoesophageal fistula: A rare complication.

Revista espanola de anestesiologia y reanimacion·2026
See all related articles

Area of Science:

  • Anesthesiology
  • Pharmacology

Background:

  • Rocuronium is a novel amino-steroidal nondepolarizing neuromuscular blocking agent (NDNMBA).
  • It presents unique pharmacokinetic and pharmacodynamic properties compared to existing agents.

Purpose of the Study:

  • To evaluate the clinical utility and safety profile of rocuronium.
  • To highlight its advantages in specific clinical scenarios requiring rapid neuromuscular blockade.

Main Methods:

  • Clinical use and efficacy assessment of rocuronium.
  • Comparison of rocuronium's properties with other NDNMBA, such as vecuronium.

Main Results:

  • Rocuronium demonstrates a rapid onset of action, ideal for tracheal intubation.
  • It exhibits greater selectivity for laryngeal muscles and lacks active metabolites.

Related Experiment Videos

  • Hemodynamic stability and absence of histamine release are noted, even at higher doses.
  • Successful applications include emergency surgery, cesarean delivery, cardiovascular surgery, and organ transplantation.
  • Rocuronium allows for predictable reversibility with repeated dosing or continuous infusion.

    • Conclusions:

    • Rocuronium is a valuable option for neuromuscular blockade, especially when rapid onset is critical.
    • Its favorable safety profile and efficacy support its use in diverse and high-risk surgical settings.