Related Experiment Videos
Midterm reversible failure in trabeculectomies with adjunctive mitomycin-C
N Kasahara1, T J Smith, S A Sibayan
1New England Glaucoma Research Foundation, Schepens Eye Research Institute.
Background And Objectives:
Trabeculectomies usually fail early (< 21 days) or late (> 6 months) when no antifibrotic agent is used. Failure is uncommon during the midterm period, between 3 weeks and 6 months. The purpose of this study is to verify the incidence of failure of trabeculectomies with mitomycin-C (MMC) during the midterm period and to evaluate the safety and efficacy of laser suture lysis (LSL) for reversing it.
Patients And Methods:
The authors reviewed the records of 130 consecutive patients who underwent trabeculectomy with adjunctive MMC.
Results:
Fourteen patients (15 eyes) had increased intraocular pressure (IOP), between 21 and 185 days (median 41 days). LSL was effective in decreasing the IOP to acceptable levels in 10 (66.6%) of the 15 eyes. No complications related to LSL were noticed.
Conclusion:
The reversibility of midterm failure seems to be a unique feature of trabeculectomies with MMC.