Peribulbar anesthesia: one versus two injections
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Updated: Aug 22, 2026

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
1Yüzüncü Yil Universitesi Tip Fakültesi, Göz Hastaliklari A.D., Van, Türkiye.
Background And Objective:
The authors describe their prospective, randomized study of a single peribulbar injection into the junction of the lateral third and medial two thirds of the lower lid compared with the standard two-injection peribulbar technique.
Patients And Methods:
One hundred twenty patients undergoing elective intraocular surgery were randomly allocated to receive either one or two injections of a mixture of balanced salt solution, 2% lidocaine, 0.5% bupivacaine, and hyaluronidase. Preoperative akinesia was assessed following the injections. At the end of surgery, the patients were asked if they had experienced any pain or discomfort during surgery.
Results:
There was no significant difference in pain or globe akinesia between the two groups.
Conclusion:
The single peribulbar injection was found to be as effective as the standard two-injection peribulbar technique.
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