[Multiple myeloma with monoclonal IgE gammopathy (author's transl)]

In a 48-year-old female patient with monoclonal gammopathy and histologically proven plasmocytoma IgE could be demonstrated in bone marrow plasma cells by means of direct immunofluorescence. Immunoelectrophoresis showed a light-chain type chi. Radiographically diffuse osteolytic skeletal lesions were found. Bence-Jones proteinuria and plasma cell leukaemia were absent. This patient represents the fourth recognized case of IgE myeloma. The chi/lambda ratio in IgE myeloma is 1:1 according to present knowledge.