Gap junctional intercellular communication in bone: a cellular basis for the mechanostat set point

Mechanically stimulated osteocytes regulate osteoblastic activity via gap junctions.

American journal of physiology. Cell physiology·2006

Mechanical stimulation effects on functional end effectors in osteoblastic MG-63 cells.

Journal of biomechanics·2005

Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells.

Bone·2004

Development of a cost-effective loading machine for biomechanical evaluation of mouse transgenic models.

Medical engineering & physics·2004

Increases in cytosolic calcium, but not fluid flow, affect aggrecan mRNA levels in articular chondrocytes.

Journal of cellular biochemistry·2003

Oscillating fluid flow regulates gap junction communication in osteocytic MLO-Y4 cells by an ERK1/2 MAP kinase-dependent mechanism.

Bone·2003

Multifactorial Regulation of Inflammatory Bone Loss in Chronic Inflammatory and Immune-Associated Disorders: Osteoimmune Mechanisms and Translational Prospects of Natural Small Molecules.

Calcified tissue international·2026

Strontium Treatment Potentiates Bone Anabolic Action of Intermittent PTH in Ovariectomized Rats.

Calcified tissue international·2026

Piezo1, Integrins, and YAP/TAZ in Osteoporotic Mechanotransduction: Key Pathways, Crosstalk, and Therapeutic Implications.

Calcified tissue international·2026

Differential Effects of a First-in-Class IKKα Inhibitor on Trabecular and Cortical Bone in a Human Prostate Cancer Xenograft Model.

Calcified tissue international·2026

Impact of Beta-Blocker Therapy for Cardiovascular Diseases on Bone Healing Following Fracture Surgery.

Calcified tissue international·2026

Teriparatide Therapy in Children with Hypoparathyroidism: A Systematic Review and Meta-Analysis.

Calcified tissue international·2026

Portable structured-light 3D volumetry for breast and flap assessment: Technical validation and workflow development.

JPRAS open·2026

Limb Salvage in a War Zone: Reconstruction of Extensive Radial Bone Loss Using a Nonvascularized Fibular Graft and Groin Flap.

Cureus·2026

Isometric points in cerclage for patellar tendon repair: a 3-dimensional, weightbearing computed tomography kinematic simulation.

Archives of orthopaedic and trauma surgery·2026

Quantifying intrinsic stress and structural strength of human clavicles from CT-derived geometry: An analytical framework.

Journal of the mechanical behavior of biomedical materials·2026

Real-time soft tissue balance assessment in total knee arthroplasty using a wireless flexible sensor array.

Medical & biological engineering & computing·2026

Assessment of Suture Tension on an Advanced Ureteral Repair Simulator Using Black Light Assessment of Surgical Technique.

Military medicine·2026

Related Experiment Videos

Gap junctional intercellular communication in bone: a cellular basis for the mechanostat set point

Related Concept Videos

Mechanically stimulated osteocytes regulate osteoblastic activity via gap junctions.

Mechanical stimulation effects on functional end effectors in osteoblastic MG-63 cells.

Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells.

Development of a cost-effective loading machine for biomechanical evaluation of mouse transgenic models.

Increases in cytosolic calcium, but not fluid flow, affect aggrecan mRNA levels in articular chondrocytes.

Oscillating fluid flow regulates gap junction communication in osteocytic MLO-Y4 cells by an ERK1/2 MAP kinase-dependent mechanism.

Multifactorial Regulation of Inflammatory Bone Loss in Chronic Inflammatory and Immune-Associated Disorders: Osteoimmune Mechanisms and Translational Prospects of Natural Small Molecules.

Strontium Treatment Potentiates Bone Anabolic Action of Intermittent PTH in Ovariectomized Rats.

Piezo1, Integrins, and YAP/TAZ in Osteoporotic Mechanotransduction: Key Pathways, Crosstalk, and Therapeutic Implications.

Differential Effects of a First-in-Class IKKα Inhibitor on Trabecular and Cortical Bone in a Human Prostate Cancer Xenograft Model.

Impact of Beta-Blocker Therapy for Cardiovascular Diseases on Bone Healing Following Fracture Surgery.

Teriparatide Therapy in Children with Hypoparathyroidism: A Systematic Review and Meta-Analysis.

Portable structured-light 3D volumetry for breast and flap assessment: Technical validation and workflow development.

Limb Salvage in a War Zone: Reconstruction of Extensive Radial Bone Loss Using a Nonvascularized Fibular Graft and Groin Flap.

Isometric points in cerclage for patellar tendon repair: a 3-dimensional, weightbearing computed tomography kinematic simulation.

Quantifying intrinsic stress and structural strength of human clavicles from CT-derived geometry: An analytical framework.

Real-time soft tissue balance assessment in total knee arthroplasty using a wireless flexible sensor array.

Assessment of Suture Tension on an Advanced Ureteral Repair Simulator Using Black Light Assessment of Surgical Technique.

Related Experiment Videos

Gap junctional intercellular communication in bone: a cellular basis for the mechanostat set point

Related Concept Videos

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