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Uncurved-DNA signals are important for translational positioning of nucleosomes
S Belikov1, A Kapranov, V Karpov
1W. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Laboratory of Structure and Function of Chromatin, Moscow, Russia.
Journal of Biomolecular Structure & Dynamics
|January 24, 1998
Abstract:
We describe here a possible mechanism for non-random arrangement of nucleosomes along genomic DNA by short stretches of uncurved DNA. Available biochemical data on nucleosome positioning on different DNA sequences were analyzed. A strong correlation between location of nucleosome borders and location of uncurved sequences along DNA was observed. Tested sequences include satellites, 5S RNA genes and 5' regions of different genes.