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[Biological effects of substances similar to salicylanilides benzanilides]
1Katedra anorganické a organické chemie Farmaceutické fakulty Univerzity Karlovy, Hradec Králové.
Abstract:
The present review paper is the first collected communication about biological activity of benzanilides. The substances of the above-mentioned structures show a number of activities (antibacterial, ref. 1-22; antituberculous, ref. 23-25; antimycotic, ref. 26-95; antiviral, ref. 96-98, antiprotozoan, ref. 97; anthelmintic, ref. 37, 99-100; insecticidal, ref. 31, 37, 101-104; herbicidal, ref. 106-130, antitumour, ref. 131-137; immunosuppressive, ref. 134, 138; hypnotic, ref. 140; anticonvulsive, ref. 141-151, anti-inflammatory, ref. 152; local-anaesthetic, ref. 155-156; antiarrhythmic, ref. 155, 158; vasodilating, ref. 159; antiulcerative, ref. 160; anti-androgenic, ref. 161; hypoglycemic ref. 162). Only very few of them have been hitherto introduced into practice. Papers investigating biological activity of benzanilides can be encountered also at present.