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Rapid identification of Mycobacterium tuberculosis complex on urine samples by Gen-Probe amplification test
D Fontana1, E Pozzi, F Porpiglia
1Department of Clinical and Biological Sciences, University of Turin, Hospital S. Luigi, Regione Gonzole, Orbassano (Turin), Italy.
Urological Research
|January 1, 1997
Summary
The Amplified Mycobacterium tuberculosis Direct Detection Test (AMTD) shows high accuracy for detecting urinary tract tuberculosis in urine samples. This rapid test aids in diagnosing tuberculosis, but results require careful interpretation alongside clinical findings.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Diagnostics
Background:
- Urinary tract tuberculosis diagnosis can be challenging.
- Rapid diagnostic methods are needed for timely treatment.
Purpose of the Study:
- To assess the Amplified Mycobacterium tuberculosis Direct Detection Test (AMTD) for urine samples.
- To evaluate AMTD's utility in diagnosing urinary tract tuberculosis.
Main Methods:
- Urine samples from 95 patients were tested using microscopy, culture, and AMTD.
- Culture was used as the reference standard for comparison.
Main Results:
- AMTD demonstrated high sensitivity (100%) and specificity (93.44%) when compared to culture.
- Positive and negative predictive values were also high (89.47% and 100%, respectively).
Conclusions:
- AMTD is a promising tool for the rapid detection of urinary tract tuberculosis.
- Clinical correlation is essential for interpreting AMTD results, especially in atypical cases.
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