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Updated: Jul 23, 2026
Platelet Adhesion and Aggregation Under Flow using Microfluidic Flow Cells
Published on: October 27, 2009
Measurement of platelet aggregation peptide inhibitors by ultrasonic interferometry
B Chabance1, P Perrotin, R Guillet
1CNRS URA 1188, Laboratoire des Protéines, Université de Paris V, Paris, France.
Abstract:
Several peptide inhibitors of thrombin- or collagen-induced platelet aggregation and of the interaction between glycoprotein Ib and von Willebrand factor were studied by a new method--ultrasonic interferometry (Echo Cell). Inhibition of aggregate formation in a concentration-dependent manner was observed. The sensitivity of the method was 3 to 40 times higher than that of classical turbidimetry.
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