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Recent application and developments of capillary isotachophoresis
1Institute of Analytical Chemistry, Academy of Sciences of the Czech Republic, Brno.
Electrophoresis
|February 10, 1998
Summary
Capillary isotachophoresis effectively concentrates trace analytes in dilute samples. This review covers advancements in capillary isotachophoresis, particularly its use with capillary zone electrophoresis from 1993-1996.
Area of Science:
- Analytical Chemistry
- Separation Science
Background:
- Capillary isotachophoresis (CITP) is a key electromigration technique.
- CITP excels at concentrating trace components from dilute samples.
Purpose of the Study:
- To review advancements in capillary isotachophoresis.
- To summarize research published between 1993 and 1996.
- To highlight CITP's role in hyphenated techniques.
Main Methods:
- Review of scientific literature from 1993-1996.
- Focus on capillary isotachophoresis applications.
- Emphasis on online coupling with capillary zone electrophoresis.
Main Results:
- CITP is predominantly used as a preliminary step for capillary zone electrophoresis.
- Significant developments in CITP applications were published during the review period.
- The method's ability to concentrate analytes was further demonstrated.
Conclusions:
- Capillary isotachophoresis remains a vital technique for trace analysis.
- Its integration with capillary zone electrophoresis offers powerful separation capabilities.
- Continued research has refined CITP's utility in complex sample analysis.