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Related Experiment Videos

Characterizing generalized anxiety: temporal and symptomatic thresholds

O J Bienvenu1, G Nestadt, W W Eaton

  • 1School of Hygiene and Public Health, Department of Mental Hygiene, Johns Hopkins University, Baltimore, Maryland 21205-1999, USA.

The Journal of Nervous and Mental Disease
|February 11, 1998
PubMed
Summary
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Generalized Anxiety Disorder (GAD) diagnosis requires specific symptom counts for a distinct epidemiologic profile. This finding impacts the construct validity of GAD in clinical research.

Area of Science:

  • Psychiatry
  • Epidemiology
  • Psychology

Background:

  • Generalized Anxiety Disorder (GAD) diagnosis requires specific symptom counts for a distinct epidemiologic profile.
  • Understanding the clinical characteristics of GAD is crucial for accurate diagnosis and treatment.
  • Previous research has not fully elucidated the demographic and comorbidity profiles associated with varying levels of anxiety pathology.

Purpose of the Study:

  • To compare demographic and comorbidity profiles of subjects with different levels of anxiety pathology.
  • To determine if clinical characteristics of DSM-III-R Generalized Anxiety Disorder (GAD) subjects differ from those with other forms of generalized anxiety.
  • To assess the construct validity of GAD based on symptom criteria.

Main Methods:

Related Experiment Videos

  • Utilized data from the 1993 follow-up of the Baltimore cohort of the Epidemiologic Catchment Area Program.
  • Employed the Diagnostic Interview Schedule to categorize subjects into five mutually exclusive symptom groups.
  • Analyzed demographic and comorbidity profiles across different anxiety symptom severity levels.

    • Main Results:

    • Subjects meeting DSM-III-R GAD criteria, or exhibiting six months or one month of anxiety with six associated symptoms, formed a homogeneous group.
    • This GAD group exhibited distinct demographic and comorbidity profiles compared to individuals with no anxiety or fewer than six symptoms.
    • The number of symptoms, not the duration or nature of worries, determined this specific epidemiologic profile.

    Conclusions:

    • Requiring six anxiety symptoms effectively identifies a group with a particular epidemiologic profile relevant to Generalized Anxiety Disorder (GAD).
    • These findings support the construct validity of GAD when defined by a specific symptom count.
    • The results suggest that symptom count is a more critical factor than symptom duration or worry content in defining the GAD profile.