[Disorders of kidney function in patients with benign prostatic hyperplasia]

Area of Science:

• Urology
• Nephrology
• Geriatrics

Background:

• Elderly men are at risk for renal dysfunction.
• Benign prostatic hyperplasia (BPH) can impact kidney function.
• Early detection of renal impairment is crucial for preventing chronic kidney disease (CKD).

Purpose of the Study:

• To evaluate an original technique for early outpatient detection of renal dysfunction in elderly men.
• To assess the prevalence of renal dysfunction in elderly men, particularly in relation to BPH.
• To compare the novel technique with established methods like radionuclide tracing and the Reberg-Tareev test.

Main Methods:

• An original renal function assessment technique based on urinary 5-NOK elimination kinetics was employed.
• 648 males aged 50 to 86 were examined.
• Results were correlated with radionuclide tracing and Reberg-Tareev test findings.

Main Results:

• Renal dysfunction was detected in 165 out of 648 patients (approximately 25.5%).
• Benign prostatic hyperplasia was identified as the underlying cause in 159 of these patients (approximately 96.4%).
• The novel technique demonstrated informative value and compatibility with radionuclide tracing and Reberg-Tareev testing.

Conclusions:

• Early detection of renal dysfunction using the 5-NOK elimination kinetics method is feasible in an outpatient setting for elderly men.
• Identifying renal dysfunction in early stages of BPH allows for timely intervention.
• Prompt treatment can prevent the progression of chronic renal failure in this patient group.