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Ivermectin toxicosis in a zebra
L A Hautekeete1, S A Khan, W S Hales
1ASPCA/National Animal Poison Control Center, Urbana, IL 61801, USA.
Veterinary and Human Toxicology
|February 19, 1998
Summary
A young zebra experienced ataxia, blindness, and depression after an accidental ivermectin overdose. Symptoms resolved within five days with supportive care, similar to ivermectin toxicity in horses.
Area of Science:
- Veterinary Neurology
- Toxicology
Background:
- Ivermectin is a widely used antiparasitic drug in veterinary medicine.
- Understanding ivermectin dosage and toxicity is crucial for safe animal treatment.
Observation:
- A 3-month-old zebra foal accidentally ingested 2.08 mg/kg of ivermectin.
- Clinical signs of toxicity appeared within hours of ingestion.
Findings:
- The zebra exhibited ataxia, temporary blindness, and depression.
- These neurological signs are consistent with ivermectin toxicosis reported in other species, notably horses.
- Full recovery occurred by day five with symptomatic and supportive treatment.
Implications:
- This case highlights the potential for ivermectin neurotoxicity in exotic equids.
- Reinforces the need for careful dose calculation and administration of ivermectin in young animals.
- Suggests that supportive care can be effective in managing ivermectin overdose in zebras.