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Related Experiment Videos

Ivermectin toxicosis in a zebra

L A Hautekeete1, S A Khan, W S Hales

  • 1ASPCA/National Animal Poison Control Center, Urbana, IL 61801, USA.

Veterinary and Human Toxicology
|February 19, 1998
PubMed
Summary
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A young zebra experienced ataxia, blindness, and depression after an accidental ivermectin overdose. Symptoms resolved within five days with supportive care, similar to ivermectin toxicity in horses.

Area of Science:

  • Veterinary Neurology
  • Toxicology

Background:

  • Ivermectin is a widely used antiparasitic drug in veterinary medicine.
  • Understanding ivermectin dosage and toxicity is crucial for safe animal treatment.

Observation:

  • A 3-month-old zebra foal accidentally ingested 2.08 mg/kg of ivermectin.
  • Clinical signs of toxicity appeared within hours of ingestion.

Findings:

  • The zebra exhibited ataxia, temporary blindness, and depression.
  • These neurological signs are consistent with ivermectin toxicosis reported in other species, notably horses.
  • Full recovery occurred by day five with symptomatic and supportive treatment.

Implications:

  • This case highlights the potential for ivermectin neurotoxicity in exotic equids.

Related Experiment Videos

  • Reinforces the need for careful dose calculation and administration of ivermectin in young animals.
  • Suggests that supportive care can be effective in managing ivermectin overdose in zebras.