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[Hepatotropic GB and G viruses]

J Aguirre García1

  • 1Unidad de Patología, Hospital General de México, SS, Facultad de Medicina, UNAM, México, D.F.

Revista De Gastroenterologia De Mexico
|April 1, 1997
PubMed
Summary

This review covers GB viruses (GBV-A, GBV-B, GBV-C), noting GBV-C/HGV is parenterally transmitted and infects over 10% of hepatitis patients, though its pathogenicity remains unclear.

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Area of Science:

  • Virology
  • Hepatology
  • Infectious Diseases

Context:

  • Review of the discovery and characteristics of GB viruses (GBV-A, GBV-B, and GBV-C).
  • Exploration of the relationship between GB Virus-C (GBV-C) and Hepatitis G Virus (HGV).
  • GBV-A and GBV-B are not associated with human liver disease.

Purpose:

  • To present a review of the discovery of GB viruses.
  • To discuss the transmission routes and prevalence of GBV-C/HGV.
  • To highlight the undefined pathogenicity of GBV-C/HGV.

Summary:

  • GB Virus-C (GBV-C), also known as Hepatitis G Virus (HGV), is transmitted parenterally via blood transfusions or contaminated needles, leading to chronic infections.
  • Prevalence of GBV-C/HGV infection is low (<1%) in blood donors but high (>10%) in patients with Hepatitis B or C.
  • The specific role and pathogenicity of GBV-C/HGV in human disease are not well-defined.

Impact:

  • Provides a consolidated overview of GB viruses, aiding researchers in understanding their discovery and implications.
  • Highlights the epidemiological significance of GBV-C/HGV in specific patient populations.
  • Underscores the need for further research into the pathogenicity of GBV-C/HGV.

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