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Contact dermatitis caused by sesquiterpene lactones
E Spettoli1, S Silvani, P Lucente
1Department of Dermatology, University of Bologna, Bologna, Italy.
Summary
Contact dermatitis from Compositae plants can affect gardeners. A case study identified sensitization to sesquiterpene lactones in both plants and pesticides, highlighting common allergens.
Area of Science:
- Dermatology
- Allergology
- Toxicology
Background:
- Compositae dermatitis commonly affects individuals with occupational exposure, such as gardeners and florists.
- This condition can also occur in individuals without direct occupational risk.
Observation:
- A 65-year-old male gardener presented with chronic facial and hand eczema.
- Symptoms recurred after exposure to fertilizers and handling plants.
Findings:
- Patch testing revealed positive reactions to sesquiterpene lactone mix, arnica tincture, pyrethrum, and captafol.
- Sesquiterpene lactones were identified as the likely cause of the patient's allergic contact dermatitis.
Implications:
- This case highlights the dual role of Compositae plants and associated pesticides as sensitizers.
- Identifying specific allergens like sesquiterpene lactones is crucial for managing Compositae dermatitis.