Related Experiment Videos
Adverse effects of amiodarone
M Jafari-Fesharaki1, M M Scheinman
1School of Pharmacy, University of California, San Francisco, USA.
Pacing and Clinical Electrophysiology : PACE
|February 25, 1998
Summary
Amiodarone, an antiarrhythmic drug, is widely used for atrial fibrillation but can cause dose-related adverse effects. This review covers amiodarone
Area of Science:
- Cardiology
- Pharmacology
Background:
- Amiodarone, initially an antianginal, is now a key antiarrhythmic.
- Its use expanded from malignant ventricular arrhythmias to atrial fibrillation rate and rhythm control.
- Prescribed by cardiologists and other medical professionals.
Purpose of the Study:
- To review the adverse effects and drug interactions of amiodarone.
- To provide recommendations for identifying and managing amiodarone-induced adverse effects.
Main Methods:
- Literature review of amiodarone's adverse effects and interactions.
- Analysis of dose-related and reversible adverse events.
- Synthesis of management strategies.
Main Results:
- Amiodarone therapy is associated with a broad spectrum of potential adverse effects.
- Most adverse effects are dose-dependent and reversible.
- Drug interactions are a significant consideration in amiodarone therapy.
Conclusions:
- Comprehensive understanding of amiodarone's adverse effects is crucial for safe and effective patient management.
- Monitoring and proactive management are essential to mitigate risks associated with amiodarone.
- This review provides a guide for healthcare professionals managing patients on amiodarone therapy.