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[Stem cell apheresis--experiences in children]
1Hämatologisches Zentrallabor der Universität, Schweiz.
Beitrage Zur Infusionstherapie Und Transfusionsmedizin = Contributions to Infusion Therapy and Transfusion Medicine
|January 1, 1994
Summary
Stem cell apheresis supports patients with malignant diseases undergoing intensive therapy. This study evaluates the safety of apheresis in pediatric patients using the Fresenius AS 104 machine.
Area of Science:
- Hematology
- Oncology
- Cellular Therapy
Context:
- Stem cell apheresis is crucial for managing patients with malignant diseases requiring intensive therapeutic regimens.
- Advancements in understanding hematopoiesis pathophysiology and cytokine function have driven progress in the field.
- Technical improvements in apheresis enable the collection of highly purified stem cell fractions.
Purpose:
- To report the safety experience of stem cell apheresis in pediatric patients (ages 1-21 years).
- To evaluate the performance of the Fresenius AS 104 apheresis machine in a pediatric setting.
Summary:
- The study details the safety of stem cell apheresis procedures performed on pediatric patients.
- The Fresenius AS 104 machine was utilized for stem cell collection in this cohort.
- While clinical outcomes are reported separately, this focuses on the safety aspects of the apheresis process.
Impact:
- Provides essential safety data for pediatric stem cell apheresis, informing clinical practice.
- Contributes to the understanding of apheresis machine safety in younger populations.
- Supports the integration of stem cell apheresis as a safe supportive care modality in pediatric oncology.