Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anion gap determination in preeclampsia

L C Matsumoto1, D S Kirz, S Shott

  • 1Mercy Hospital and Medical Center, Chicago, Illinois, USA.

Obstetrics and Gynecology
|March 10, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The safety and efficacy of pediatric lingual tonsillectomy.

International journal of pediatric otorhinolaryngology·2016
Same author

Utility of a Paediatric Bleeding Questionnaire as a screening tool for von Willebrand disease in apparently healthy children.

Haemophilia : the official journal of the World Federation of Hemophilia·2015
Same author

Lower initial dose desoxycorticosterone pivalate for treatment of canine primary hypoadrenocorticism.

Australian veterinary journal·2013
Same author

In vivo measurement of the subchondral bone thickness of lumbar facet joint using magnetic resonance imaging.

Osteoarthritis and cartilage·2010
Same author

Bone mineral density in the proximal tibia varies as a function of static alignment and knee adduction angular momentum in individuals with medial knee osteoarthritis.

Bone·2006
Same author

The radiographic joint space width in clinically normal hips: effects of age, gender and physical parameters.

Osteoarthritis and cartilage·2003
Same journal

The Political Determinants of Obstetric Prescribing.

Obstetrics and gynecology·2026
Same journal

Glucagon-Like Peptide-1 Receptor Agonists and Risk of Adverse Maternal Pregnancy Outcomes: A Systematic Review and Meta-analysis.

Obstetrics and gynecology·2026
Same journal

Milestones in Motion: Vaginal Birth After Cesarean.

Obstetrics and gynecology·2026
Same journal

Ebola Virus in Pregnancy.

Obstetrics and gynecology·2026
Same journal

A Quality-Improvement Study Evaluating Three Postpartum Prophylactic Oxytocin Rates and Blood Loss After Vaginal Birth.

Obstetrics and gynecology·2026
Same journal

The Effects of Climate Change on Obstetric and Gynecologic Health.

Obstetrics and gynecology·2026
See all related articles

Pregnant women with proteinuric hypertension showed a smaller calculated anion gap compared to those without hypertension. This finding suggests a potential biomarker for hypertensive disorders during pregnancy.

Area of Science:

  • Obstetrics and Gynecology
  • Clinical Chemistry
  • Renal Physiology

Background:

  • Hypertension in pregnancy, including preeclampsia, is a significant concern.
  • The anion gap is an indirect measure of unmeasured anions in serum.
  • Understanding metabolic changes in hypertensive pregnancies is crucial.

Purpose of the Study:

  • To investigate the relationship between hypertension in pregnancy and the calculated anion gap.
  • To compare anion gap values in pregnant women with and without hypertension.

Main Methods:

  • Retrospective analysis of 1223 deliveries over a 6-month period.
  • Categorization of patients into proteinuric hypertension, non-proteinuric hypertension, and normotensive groups.
  • Statistical comparison of anion gap, serum sodium, chloride, and bicarbonate using Kruskal-Wallis and Mann-Whitney tests.

Related Experiment Videos

Main Results:

  • Proteinuric hypertensive patients exhibited significantly lower serum sodium levels (P < .005).
  • A statistically significant lower anion gap was observed in proteinuric hypertensive patients (P < .005).
  • No significant differences in serum chloride or bicarbonate levels were found between groups.

Conclusions:

  • The anion gap is reduced in pregnant women with proteinuric hypertension.
  • This suggests potential alterations in acid-base balance or unmeasured anions in this condition.
  • The anion gap may serve as a useful indicator in managing hypertensive disorders of pregnancy.