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[Long-term follow up of QRS axis deviation]
M Yoshikawa1, Y Uematsu, M Nagasawa
1Department of Clinical Laboratory, Institute for Adult Diseases, Asahi Life Foundation, Tokyo.
Rinsho Byori. the Japanese Journal of Clinical Pathology
|March 11, 1998
Summary
Aging causes QRS axis deviation due to degenerative changes in the heart's electrical pathways. This study explored potential links between aging, body shape, and QRS axis deviation, finding pathway degeneration to be a key factor.
Area of Science:
- Cardiology
- Physiology
- Gerontology
Context:
- QRS axis deviation is associated with aging and cardiac conditions like bundle branch block.
- Extra-cardiac factors such as body weight and cardiac-thoracic ratio were hypothesized to influence QRS axis deviation with aging.
Purpose:
- To investigate the relationship between aging, extra-cardiac factors (body weight, cardiac-thoracic ratio), and QRS axis deviation.
- To identify the primary causes of QRS axis deviation in aging individuals.
Summary:
- This study examined 28 patients with QRS axis deviation, comparing body weight and cardiac-thoracic ratio against the degree of deviation, with no significant correlation found.
- Left anterior hemiblock (LAH) was identified in 8 out of 27 left axis deviation (LAD) patients.
- Pathological findings indicate that age-related degeneration of the cardiac stimulation pathway contributes to bundle branch block and subsequent QRS axis deviation.
Impact:
- Suggests that age-related degeneration of the left anterior stimulation pathway is a significant cause of QRS axis deviation.
- Highlights the importance of considering electrophysiological changes with aging in diagnosing cardiac abnormalities.
- Provides insights into the underlying mechanisms of QRS axis deviation, differentiating it from morphological changes.