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Systemic sarcoidosis with bilateral orbital involvement: MR findings
E M Simon1, G H Zoarski, M I Rothman
1Department of Diagnostic Radiology, University of Maryland Medical Center, Baltimore 21201, USA.
AJNR. American Journal of Neuroradiology
|March 21, 1998
Summary
Ocular sarcoidosis can cause double vision and abnormal eye movements. Magnetic resonance imaging (MRI) revealed characteristic muscle and gland changes, confirming the diagnosis and guiding successful treatment.
Area of Science:
- Ophthalmology
- Neurology
- Rheumatology
Background:
- Ocular involvement in sarcoidosis can present with diverse clinical manifestations.
- Early diagnosis and treatment are crucial for managing sarcoidosis-related eye conditions.
Observation:
- A 43-year-old woman presented with diplopia and disconjugate gaze.
- Physical examination revealed abnormal eye movements.
- Magnetic resonance (MR) imaging demonstrated enlarged, enhancing extraocular muscles and lacrimal glands bilaterally.
Findings:
- Biopsy confirmed sarcoidosis as the underlying cause.
- Chest imaging (radiographs and CT scans) did not reveal systemic involvement.
- The patient showed clinical and MR imaging improvement following medical therapy.
Implications:
- This case highlights the importance of considering sarcoidosis in patients with unexplained extraocular muscle and lacrimal gland abnormalities.
- Multimodal imaging, including MRI, is valuable for diagnosing and monitoring ocular sarcoidosis.
- Prompt treatment can lead to significant recovery of visual function and reduction of symptoms.