Primary intracranial rhabdomyosarcoma producing proptosis

Area of Science:

• Neuro-oncology
• Pediatric oncology
• Pathology

Background:

• Primary rhabdomyosarcoma is a rare malignant tumor.
• Subfrontal tumors can present with neurological symptoms.

Observation:

• A 16-year-old female presented with headache and proptosis.
• Imaging revealed a right subfrontal neoplasm involving dura, frontal sinus, and orbit.

Findings:

• A circumscribed, demarcated primary rhabdomyosarcoma was diagnosed.
• The tumor invaded adjacent structures, including the frontal sinus and orbital roof.

Implications:

• This case highlights the importance of considering rare tumors in pediatric neuro-oncology.
• The findings suggest a potential link between mesenchymal differentiation and neuroepithelial origins for such tumors.