Tail tip necrosis in two litters of Birman kittens

The development of tail tip necrosis in two litters of Birman kittens from the same queen is described. On the basis of blood group testing of the queen and one of the stud cats, a presumptive diagnosis of neonatal isoerythrolysis involving cold-acting agglutinins was made. It is suggested that on presentation of tail tip necrosis in kittens a diagnosis of neonatal isoerythrolysis or isoagglutination should be considered.