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Lichen planus associated with hepatitis C

D J Schissel1, D M Elston

  • 1Department of Dermatology, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA.

Cutis
|March 27, 1998
PubMed
Summary
This summary is machine-generated.

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The cause of lichen planus is unknown, but this case links chronic hepatitis C to widespread hypertrophic lichen planus. This finding suggests a potential association between this liver disease and a severe form of lichen planus.

Area of Science:

  • Dermatology
  • Hepatology
  • Immunology

Background:

  • Lichen planus is an inflammatory condition with unknown etiology.
  • Oral erosive lichen planus has been previously associated with liver disease.
  • Hepatitis C virus infection is a significant global health concern.

Observation:

  • A patient developed widespread hypertrophic lichen planus.
  • The patient had a history of chronic hepatitis C infection acquired via blood transfusion.
  • This presentation is unusual given the typical association of oral erosive lichen planus with liver disease.

Findings:

  • This case report details a patient with chronic hepatitis C who developed widespread hypertrophic lichen planus.
  • The findings suggest a potential link between hepatitis C virus infection and the development of severe cutaneous lichen planus.

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  • The specific mechanism underlying this association remains to be elucidated.
  • Implications:

    • This case highlights a potential, albeit rare, dermatological manifestation of chronic hepatitis C.
    • Further research may be warranted to explore the immunological links between hepatitis C virus and lichen planus.
    • Clinicians should consider screening for hepatitis C in patients presenting with severe or unusual forms of lichen planus.